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  • Introduction
  • Bacterial Epigenetics
  • Topics
  • Restriction-Modification (RM) Systems
  • Flavors of RM Systems
  • Type II Subtypes
  • Traditional Characterization Methods
  • SMRT Sequencing for RM Characterization
  • Number of MTases Characterized
  • Early Results of SMRT-Based Characterization
  • General Approach
  • Results-M.EcoKI Plasmid Clone (Type I)
  • Results-M.BceJI Plasmid Clone (Type III)
  • General Approach
  • Motif Summary 4 Bibersteinia Strains
  • Bibersteinia MTase Genes
  • Bibersteinia MTase Genes Cloned
  • Matching Clones with Activities
  • Differences Between Genome and Clone SMRT Modification/Motif Data
  • Conclusions 1
  • Bacterial MTases with Non-RM Functions
  • Phylogenetic Profiles of DNA MTases
  • "Persistant" MTases
  • Conclusions 2
  • Acknowledgments
  • Thank You
  • Q & A
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  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs
  • Speaker: Brian Anton, Phd / New England BioLabs