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  • Introduction
  • PacBio RS II and Sequel System Install Base
  • Chemistry & Software Improvements
  • Sequel System
  • Multiplexed Bacterial De Novo Assembly
  • Long Read Sequencing Articles
  • Shotgun Metagenomics
  • Bacterial Iso-Seq
  • Plant & Animal Genomics
  • Quinoa Genome
  • Human - Targeted Sequencing Opportunities
  • High Consensus Accuracy
  • Multi- vs Single-Molecule Consensus
  • CYP2D6
  • Efficient & Scalable Two-Step Barcoding Scheme
  • Target & Sample Multiplexing
  • CYP2D6 - Neighboring pseudogene, 97% homology
  • NGS Dead Zone
  • Long Homonucleotide Stretches
  • GC-Rich Regions
  • Amplification-Free Targeted Enrichment
  • Probe-Base Enrichment
  • Phasing Variants Over Large Distances
  • Importance of Variant Phasing
  • Resolution of Structural Variation
  • PacBio Solutions in Virology - HIV/HCV
  • Pacbio Minor Variant Caller
  • Novel Colorectal Cancer Biomarkers
  • Improved Protocol for Iso-Seq on Sequel
  • Single Cell Iso-Seq
  • WGS - Structural Variation & Disease
  • Structural Variants in Stanford CG Study
  • PacBio SV Caller Development
  • Visualizing PacBio Reads in IGV
  • Improved Resolution of Difficult Regions
  • Human De Novo Genome Assemblies
  • Sequel Roadmap
  • De Novo Human Genomes
  • Cost Per Genome Dilemma (Quantity vs. Quality)
  • Sequel Roadmap - Human WGS
  • Sequel System Investment
  • >2000 Publications
  • SMRT Sequencing Characteristics
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  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio
  • Speaker: Jonas Korlach, Chief Scientific Officer / PacBio