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  • Introduction
  • The Value of De Novo, Finished Microbial Genomes
  • Hybrid Solutions for De Novo Assemblies
  • Non-Hybrid Strategy for De Novo Assemblies
  • Hierarchical Genome Assembly Process (HGAP)
  • HGAP Example Meiothermus Ruber
  • High Consensus Accuracy
  • Lack of GC Bias - High GC
  • Lack of GC Bias - Low GC
  • Requirements for Achieving High-Quality Finished Genomes
  • Finished Genomes in Infectious Disease
  • The Pertussis Genome is Extremely Repetitive
  • Complete Pertussis Genomes
  • Finished Pertussis Genomes
  • Genome Organization Comparison
  • Organization of Virulence Genes Differs Between Strains
  • Phylogeny
  • Large Structural Variations
  • High Mobile Element Diversity
  • Foodborne Pathogens
  • 100K Foodborne Pathogen Genome Project
  • Public Health Outcomes
  • Salmonella Phylogenomics
  • Salmonella HGAP Assemblies
  • Addressing Active Outbreaks with Finished Genomes
  • Epigenome Information
  • Salmonella Strains Epigenome Diversity
  • Salmonella Epigenomes
  • Listeria monocytogenes Epigenomes
  • De Novo Genome & Epigenome from a Single SMRT Cell
  • Acknowledgements
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  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio
  • Speaker: Jonas Korlach, PhD / PacBio